La investigación cognitiva del síndrome esquizofrénico
DOI:
https://doi.org/10.55414/m0w4jv49Palabras clave:
Esquizofrenia, Déficit cognitivos , Síntomas clínicos, Paradigmas experimentales, InvestigaciónResumen
Se revisan las anomalías cognitivas observadas en la esquizofrenia y, específicamente, los déficit encontrados en diversos procesos automáticos y controlados: el filtrado de la información, la atención y vigilancia, la formación de conceptos y la memoria. Se describen también diversos paradigmas experimentales utilizados para el estudio de los procesos ejecutivos centrales; y, finalmente, se describe un modelo cognitivo para las conductas anormales y los síntomas clínicos de la esquizofrenia (delirios, desorganización, alucinaciones y la pérdida del sentimiento de identidad personal) que sugiere que pueden estar ligados a un trastorno básico de la percepción holística o la interpretaciónde contextos.
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Referencias
Anscombe, R. (1987). The disorder of consciousness in schizophrenia. Schizophrenia Bulletin, 13, 241-259.
Barch, D.M. (2005). The cognitive neuros-cience of schizophrenia. Annual Review of Clinical Psychology, 1, 321-353.
Barch, D.M., Carter, C.M., MacDonald, A.W., Braver, T.S. y Cohen, J.D. (2003). Context processing deficits in schizophrenia: Diagnostic specificity, 4-week course and relationship to clinical symptoms. Journal of Abnormal Psychology, 112, 132-143.
Barch, D.M., Mitropoulou, V., Harvey, P., New, A.S., Silverman, J.M. y Siever, L.J. (2004). Context processing deficits in schizotypal personality disorder. Journal of Abnormal Psychology, 113, 556-568.
Baruch, I., Hemsley, D.R. y Gray, J. (1988). Differential performance of acute and chronic schizophrenics in a latent inhibition task. Journal of Nervous and Mental Disease, 176, 598-606.
Bentall, R.P. (1992). Reconstructing schizophrenia. Londres: Routledge.
Braff, D.L. (2004). Psychophysiological and information processing approaches to schizophrenia. En D.S. Charney y E.J. Nestler (Eds.), Neurobiology of mental illness (2nd ed.) (págs. 324-338). Nueva York: Oxford University Press.
Cohen, J. (1988). Statistical power analysis for the behavioral sciences (2nd Ed.). Hillsdale, NJ: Erlbaum.
Cohen, J.D. y Servan-Schreiber, D. (1992). Context, cortex, and dopamine: A connectionist approach to behavior and biology in schizophrenia. Psychological Review, 99, 45-77.
Crow, T.J., Done, D.J. y Sacker, A. (1995). Childhood precursors of psychosis as clues to its evolutionary origins. European Archives of Psychiatry and Clinical Neuroscience, 245, 61-69.
Chapman, L.J., Chapman, J.P., Kwapil, T.R., Eckblad, M. y Zinser, M.C. (1994). Putatively psychosis-prone subjects 10 years later. Journal of Abnormal Psychology, 103, 171-183.
David, A.S. y Cutting, J.C. (1994). The neu-ropsychology of schizophrenia. Hove, UK: Erlbaum.
Done, D.J., Crow, T.J., Jonhstone, E.C. y Sacker, A. (1994). Childhood antecedents of schizophrenia and affective illness: Social adjustment at ages 7 to 11. British Medical Journal, 309, 699-703.
Friedman, L., Kenny, J.T., Jesberger, J.A., Choy, M.M. y Meltzer, H.Y. (1995). Relationship between smooth pursuit eye-tracking and cognitive performance in schizophrenia. Biological Psychiatry, 37, 265-272.
Frith, C.D. (1979). Consciousness, infor-mation processing and schizophrenia. British Journal of Psychiatry, 134, 225-235.
Frith, C.D. (1992). The cognitive neuropsy-chology of schizophrenia. Hove, UK: Erlbaum.
Frith, C.D. y Done, J. (1988). Towards a neuropsychology of schizophrenia. British Journal of Psychiatry, 153, 437-443.
Garety, P.A. y Hemsley, D.R. (1994). Delusions: Investigations into the psychology of delusional reasoning. Hove, UK: Psychology Press.
Goldman-Rakic, P.S. (1991). Prefrontal cortical dysfunction in schizophrenia: The relevance of working memory. En B. J. Carroll y J. E. Barrett (Eds.), Psychopathology and the brain (págs. 1-23). Nueva York: Raven Press.
Goldstein, J.M., Seidman, L.J., Buka, S.L., Horton, N.J., Donatelli, J.L., Rieder, R.O., y cols. (2000). Impact of genetic vulnerability and hypoxia on overall intelligence by age 7 in offspring at high risk for schizophrenia compared with affective psychoses. Schizophrenia Bulletin, 26, 323-334.
Gray, J.A. (1982). The neuropsychology of anxiety: An enquiry into the functions of the septohippocampal system. Oxford: Oxford University Press.
Gray, J.A., Feldon, J., Rawlins, J.N.P., He-msley, D.R. y Smith, A.D. (1991). The neuropsychology of schizophrenia. Be-havioral and Brain Sciences, 14, 1-84.
Green, M., Kern, R., Braff, D. y Mintz, J. (2000). Neurocognitive deficits and functional outcome in schizophrenia: Are we measuring the “right stuff”. Schizophrenia Bulletin, 26, 119-136.
Häfner, H. y Gattaz, W. F. (Eds.). (1995). Search for the causes of schizophrenia (Vol. 3). Berlin: Springer-Verlag.
Harvey, P.D. (2001). Vulnerability to schizophrenia in adulthood. En R.E. Ingram y J.M. Price (Eds.), Vulnerability to psychopathology: Risk across lifespan (pp. 355-381). Nueva York: Guilford Press.
Heinrichs, R.W. (2004). Meta-analysis and the science of schizophrenia: Variant evidence or evidence of variants? Neuroscience and Biobehavioral Reviews, 28, 279-394.
Hemsley, D.R. (1987). An experimental psychological model for schizophrenia. En H. Häfner, W.F. Gattaz y W. Janzarik (Eds.), Search for the causes of schizophrenia (págs. 179-188). Berlín: Springer-Verlag.Hemsley, D.R. (1994). Perceptual and cognitive abnormalities as the bases for schizophrenic symptoms. En A. S. David y J. C. Cutting (Eds.), The neuropsychology of schizophrenia (págs. 97-116). Hove: Erlbaum.
Hemsley, D.R. (2005a). The development of a cognitive model of schizophrenia: Placing it in context. Neuroscience and Biobehavioral Reviews, 29, 977-988.
Hemsley, D.R. (2005b). The schizophrenic experience: Taken out of context? Schizophrenia Bulletin, 31, 43-53.
Javitt, D.C., Shelley, A., Silipo, G. y Lieberman, J.A. (2000). Deficits in auditory and visual context-dependent processing in schizophrenia. Archives of General Psychiatry, 57, 1131-1137.
Jones, P., Guth, C., Lewis, S. y Murray, R. (1994). Low intelligence and poor educational achievement precede early onset schizophrenic psychosis. En A. S. David y J. C. Cutting (Eds.), The neuropsychology of schizophrenia (págs. 131-144). Hove: Erlbaum.
Jones, P.B. (1999). Longitudinal approaches to the search for the causes of schizophrenia: Past, present and future. En W. T. Gattaz y H. Häfner (Eds.), Search for the causes of schizophrenia. IV: Balance of the century (págs. 91-119). Berlin: Springer.
Jones, P.B., Rodgers, B., Murrray, R.M. y Marmot, M.G. (1994). Child developmental risk factors for adult schizophrenia in the British 1946 birth cohort. Lancet, 344, 1398-1402.
Kamin, L.J. (1969). Predictability, surprise, attention and conditioning. En B. A. Campbell y R. M. Church (Eds.), Punishment and aversive behavior (págs. 279-296). Nueva York: Appleton Century Crofts.
Kendell, R.E., McInneny, K., Juszczak, E. y Bain, M. (1999). Obstetric complications: A reappraisal. En W. F. Gattaz y H. Häfner (Eds.), Search for the causes of schizophrenia. IV: Balance of the century (págs. 121-127). Berlin: Springer.
Kremen, W.S. y Hoff, A.L. (2004). Neurocognitive deficits in the biological relatives of individuals with schizophrenia. En W. S. Stone, S. V. Faraone y M. T. Tsuang (Eds.), Early clinical intervention and prevention in schizophrenia (págs. 133-158). Totowa, NJ: Humana Press.
Kremen, W.S., Seidman, L.J., Pepple, J.R., Lyons, M.J., Tsuang, M.T. y Faraone, S.V. (1994). Neuropsychological risk indicators for schizophrenia: A review of family studies. Schizophrenia Bulletin, 20, 103-119.
Kwapil, T.R., Miller, M.B., Zinser, M.C., Chapman, J. y Chapman, L.J. (1997). Magical ideation and social anhedonia as predictors of psychosis proneness: A partial replication. Journal of Abnormal Psychology, 106, 491-495.
Lewis, M.S. (1989). Age incidence and schizophrenia: Part 1. The season of birth controversy. Schizophrenia Bulletin, 15, 59-73.
Lubow, R.E. y Gewirtz, J.C. (1995). Latent inhibition in humans: Data, theory, and implications for schizophrenia. Psycho-logical Bulletin, 117, 87-103.
Lubow, R.E., Weiner, I. y Feldon, J. (1982). An animal model of attention. En M.Y. Speigelstein y A. Levy (Eds.), Behavioural models and the analysis of drug action(págs. 89-107). Amsterdam: Elsevier.
MacDonald, A.W. y Carter, C.S. (2003). Event related fMRI study of context processing in dorsolateral prefrontal cortex of patient with schizophrenia. Journal of Abnormal Psychology, 112, 689-697.
Magaro, P.A. (1984). Psychosis and schizo-phrenia. En W.D. Spaulding y J.K. Cole (Eds.), Theories of schizophrenia and psychosis (pp. 157-230). Lincoln, NB: University of Nebraska Press.
Maher, B.A. (1983). A tentative theory of schizophrenia utterance. En B.A. Maher y W.B. Maher (Eds.), Progress in experimental personality research (Vol. 12) (págs. 1-52). Nueva York: Academic Press.
Maher, B.A. (1988). Anomalous experience and delusional thinking: The logic of explanations. En T.F. Oltmanns y B.A. Maher (Eds.), Delusional beliefs (págs. 15-33). Nueva York: Wiley.
Malmberg, A., Lewis, G., David, A. y Allebeck, P. (1998). Premorbid adjustment and personality in people with schizophrenia. British Journal of Psychiatry, 172, 308-313.
Marenco, S. y Weinberger, D.R. (2004). Obstetric risk factors for schizophrenia and their relationship to genetic predisposition: Following Ariadne’s double-stranded thread through early development. En W.S. Stone, S.V. Faraone y M.T. Tsuang (Eds.), Early clinical intervention and prevention in schizophrenia (págs. 43-71). Totowa, NJ: Humana Press.
Morrison, A.P. (1998). A cognitive analysis of the maintenance of auditory hallucinations: Are voices to schizophrenia what bodily sensations are to panic? Behavioural and Cognitive Psychotherapy, 26, 289-302.
Morrison, A.P. (2001). The interpretation of intrusions in psychosis: An integrative cognitive approach to hallucinations and delusions. Behavioural and Cognitive Psychotherapy, 29, 257-276.
Nuechterlein, K.H. y Dawson, M.E. (1984). Information processing and attentional functioning in the developmental course of schizophrenic disorders. Schizophrenia Bulletin, 10, 160-203.
O’Callaghan, E., Sham, P., Takei, N., Glover, G. y Murray, R.M. (1991). Schizophrenia after pretatal exposure to 1957 A2 influenza epidemic. Lancet, 337, 1248-1250.
Olin, S.S., Raine, A., Cannon, T.D., Parnas, J., Schulsinger, F. y Mednick, S.A. (1997). Childhood behavior precursors of schizotypal personality disorder. Schizophrenia Bulletin, 23, 93-103.
Peters, E.R., Kent, A., Irani, M., Day, S., Pickering, A.D., Glasper, A.S., y cols. (2000). The relationship between cognitive inhibition and psychotic symptoms. Journal of Abnormal Psychology, 109, 386-395.
Posner, M. (1982). Cumulative development of attentional theory. American Psychologist, 37, 168-179.
Rantakallio, P., Jones, P., Moring, J. y von Wendt, L. (1997). Association between central nervous system infections during childhood and adult onset schizophrenia and other psychoses: A 28-year follow-up. International Journal of Epidemiology, 26, 837-843.
Schiffman, J., Carter, J., Machón, R.A. y Mednick, S. (2004). Early environmental determinants of schizophrenia. En W.S. Stone, S.V. Faraone y M.T. Tsuang (Eds.), Early clinical intervention and prevention in schizophrenia (págs. 23-41). Totowa, NJ: Humana Press.
Schmajuk, N. (2005). Brain-behaviour relationships in latent inhibition: A computational model. Neuroscience and Biobehavioral Reviews, 29, 1001-1020.
Schneider, W. y Shiffrin, R. (1977). Controlled and automatic human information processing: I. Detection, search, and attention. Psychological Review, 84, 1-66.
Silverstein, S.M. y Schenkel, I.S. (1997). Schizophrenia as a model of context deficient cortical computation. Behavioral and Brain Sciences, 20, 696-697.
Sokolov, E.N. (1960). Neuronal models and the orienting reflex. En M.A.B. Brazier (Ed.), The central nervous system and behaviour. Nueva York: Macy Foundation.
Stratta, P., Daneluzzo, E., Bustinim, M., Prosperini, P. y Rossi, A. (2000). Processing of context information in schizophrenia: Relationship to clinical symptoms and WCST performance. Schizophrenia Research, 44, 57-67.
Susser, E., Neugebauer, R., Hoek, H.W., Brown, A.S., Lin, S., Labovitz, D. y cols. (1996). Schizophrenia after prenatal famine: Further evidence. Archives of General Psychiatry, 53, 25-31.
van den Bosch, R.J. (1995). Context and cognition in schizophrenia. En J.A. den Boer, H.G.M. Westenberg y H.M. Van Praag (Eds.), Advances in the neurobiology of schizophrenia (págs. 343-366). Chichester: Wiley.
van Os, J. y Selten, J.P. (1998). Prenatal exposure to maternal stress and later schizophrenia: The May 1940 invasion of the Netherlands. British Journal of Psychiatry, 172, 324-326.
Venables, P.H. (1984). Cerebral mechanisms, autonomic responsiveness and attention to schizophrenia. En W.D. Spaulding y J.K. Cole (Eds.), Theories of schizophrenia and psychosis (págs. 47-91). Lincoln, NB: University of Nebraska Press.
Verdoux, H. y van Os, J. (2002). Psychotic symptoms in non-clinical populations and the continuum of psychosis. Schizophrenia Research, 54, 59-65.
Verdoux, H., van Os, J., Maurice-Tison, S., Gay, B., Salamon, R. y Bourgeois, M. (1999). Increased occurrence of depression in psychosis-prone subjects: A follow-up study in primary care settings. Comprehensive Psychiatry, 40, 462-468.
Walker, E. y Hochman, K.M. (2004). The nature and origin of socioemotional deficits in schizophrenia. En W.S. Stone, S.V. Faraone y M.T. Tsuang (Eds.), Early clinical intervention and prevention in schizophrenia (págs. 159-177). Totowa, NJ: Humana Press.
Walker, E.F., Grimes, K.E., Davis, D.M. y Smith, A.J. (1993). Childhood precursors of schizophrenia: Facial expressions of emotion. American Journal of Psychiatry, 150, 1654-1660.
Walker, E.F. y Lewine, R.J. (1990). Prediction of adult-onset schizophrenia from childhood home movies of patients. American Journal of Psychiatry, 147, 1052-1056.
Weinberger, D.R. (1995). From neuropathology to neurodevelopment. Lancet, 346, 552-557.
Weiner, I. (2003). The two headed latent inhibition model of schizophrenia: Modelling positive and negative symptoms and their treatment. Psychopharmacology, 169, 257-297.
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